Technical Specifications

Detailed technical parameters and product description for professional evaluation.

The H7 antigen in Avian Influenza Virus (AIV) is another important serotype, especially subtypes such as H7N9, which significantly affects both poultry and humans.

Characteristics and antigenicity

Characteristics Genomic structure: The H7 antigen belongs to the Influenza A Virus, whose genome consists of eight single-stranded negative-stranded RNA segments, each encoding one or more proteins. The H7 antigen mainly involves the Hemagglutinin (HA) protein, which is responsible for viral adhesion and entry into host cells. Hemagglutinin protein: The HA protein is a glycoprotein on the surface of the virus and is classified into 16 serotypes (H1-H16), of which H7 is one. HA proteins are responsible for binding to receptors on the surface of host cells and mediate viral entry into the cell. Antigenic variation: Avian influenza viruses are susceptible to antigenic drift and antigenic switching, leading to the emergence of new subtypes and epidemics. H7N9 is one of the most representative and pathogenic H7 subtypes. Immunogenicity: H7 antigens are highly immunogenic and can induce the host to produce neutralising antibodies against HA proteins. Neutralising antibodies prevent the virus from entering host cells, thus providing immune protection. Cross-reactivity: There may be some cross-immunity between different H7 subtypes, but usually the cross-protection is limited. Immune escape is more prevalent due to antigenic variation, posing a challenge to vaccine development.

Clinical symptoms and disease severity

Symptoms in poultry Highly pathogenic avian influenza (HPAI): Acute onset: onset within a short period of time after infection, with a rapid course of the disease. High mortality: Mortality rate up to 90-100%, especially in chickens and turkeys. Typical symptoms: depression, loss of appetite, respiratory distress, dysentery, haemorrhage and oedema of the crown and meat beard. Low Pathogenic Avian Influenza (LPAI): Mild symptoms: mild respiratory symptoms such as coughing, sneezing, tearing. Decrease in egg production: significant decrease in egg production in infected hens. Human symptoms Flu-like symptoms: fever, cough, sore throat, muscle aches, headache. Severe symptoms: severe pneumonia, acute respiratory distress syndrome, multiple organ failure. Highly pathogenic H7 subtype infected people deteriorate rapidly and have a high mortality rate.

Routes of transmission

Direct contact: Poultry-to-poultry transmission: transmitted through direct contact with infected poultry or their secretions and excretions. Human-poultry contact: humans are infected with the virus through direct contact with infected poultry or their secretions and excretions. Environmental transmission: The virus can be spread indirectly through contaminated water, feed, utensils, etc. Airborne: The virus can be transmitted through airborne droplets, especially in confined and poorly ventilated environments.

Clinical Diagnosis

Clinical symptom observation: Initial diagnosis is based on typical symptoms in poultry or humans. Laboratory Tests: PCR: Detection of viral RNA in respiratory samples by reverse transcription PCR (RT-PCR) is a rapid and sensitive test. Virus isolation: Virus is isolated from sick birds or patient samples for culture and identification of the virus. Serological testing: Detection of antibodies in serum using haemagglutination inhibition (HI) or enzyme-linked immunosorbent assay (ELISA) for assessment of infection and immune response. Rapid diagnostic reagents: Use of rapid antigen detection kits for initial screening, but laboratory confirmation is required.

Preventive measures

Preventive measures Vaccination: Vaccinate poultry with avian influenza vaccines against H7 subtypes, especially in high-risk areas. Regularly update the vaccine strain to cope with antigenic variation of the virus. Biosecurity measures: Strictly implement biosecurity measures including quarantine of newly introduced poultry, disinfection of personnel and equipment, and restriction of entry and exit of personnel and vehicles to poultry farms. Regularly monitor the disease situation inside and outside the poultry farm and take timely preventive and control measures.

Management Measures

All-in-all-out: Adopt an all-in-all-out feeding management mode to avoid mixing of different batches of poultry. It helps to reduce the spread of virus among poultry. Isolation and quarantine: newly introduced poultry should be isolated and quarantined to ensure that they are not infected with H7 subtype virus. Regular health checks should be conducted to detect and treat infected poultry in a timely manner. Personnel training: Raise awareness and preventive and control skills of keepers and veterinarians on H7 subtype avian influenza.

Therapeutic measures

There is no specific drug against H7 subtype avian influenza virus infection. The mainstay of treatment is symptomatic, providing supportive care and proper nutrition. The use of antiviral drugs such as oseltamivir (Tamiflu) and zanamivir (Relenza) may help to alleviate the symptoms but have limited effect.

Control measures

Culling of infected poultry: Rapidly cull infected and suspected infected poultry to prevent spread of the virus. Thoroughly clean and disinfect contaminated environment, equipment and utensils. Strict control of poultry trade: Restrict or prohibit the trade of poultry and poultry products in areas affected by the outbreak to prevent the spread of the virus.

Avian Influenza Virus H7 Antigen Rapid Test

Antigenne has developed the Avian Influenza Virus H7 Antigen Rapid Test, which is a fast, easy-to-use and highly accurate test that can effectively help users to detect relevant viral infections.

Key Features of SaberVet Avian Influenza Virus H7 Antigen Rapid Test

Advanced diagnostic technology designed for accuracy, simplicity, and reliability in veterinary practice.

High Accuracy

Clinical performance with 99% sensitivity and specificity, ensuring reliable diagnostic results for professional veterinary use.

Rapid Results

Get accurate diagnostic results in just 5-10 minutes without any laboratory equipment or complex procedures.

Easy to Read

Clear visual results with distinct color lines that are easy to interpret, reducing the chance of reading errors.

Testing Procedure

Simple 4-step process for accurate veterinary diagnostic results.

1

Sample Collection

Collect serum, plasma, or whole blood sample using provided collection tools.

2

Add Sample

Drop 2-3 drops of sample into the sample well on the test cassette.

3

Wait for Results

Allow 5-10 minutes for the test to develop at room temperature.

4

Read Results

Interpret the results based on the presence or absence of colored lines.

Result Interpretation

Positive

Two colored lines appear (C and T lines)

Negative

Only control line (C) appears

Invalid

No control line appears - repeat test

Quality Standards & Certifications

ITGen maintains the highest quality standards with comprehensive certifications and batch consistency guarantees.

Certifications & Standards

ISO 9001

Management System

GMP

Good Manufacturing

CE

European Conformity

ISO 13485

Approved Standards

Quality Guarantees

Batch Consistency

Every batch tested for consistent performance

Quality Control

Rigorous QC testing at every production stage

Traceability

Complete batch tracking and documentation

Performance Metrics

Sensitivity 99.2%

Specificity 98.8%

Accuracy 99.0%

Reproducibility 97.5%

8 Years of proven excellence in veterinary diagnostics manufacturing

Custom Solutions & Bulk Sourcing

Comprehensive OEM/ODM services with flexible bulk pricing and global logistics support for business partners.

OEM/ODM Services

Custom Brand Packaging
Private Label Solutions
Product Customization
Design Modifications

Bulk Pricing

Volume Discounts
Tiered Pricing Structure
Long-term Contracts
Flexible Payment Terms

Global Logistics

Worldwide Shipping
Fast Delivery Options
Cold Chain Logistics
Documentation Support

Partnership Benefits

48-Hour Quote Response

Fast turnaround time for all inquiries and custom requirements.

24/7 Technical Support

Comprehensive technical assistance and product training.

Quality Assurance

ISO GMP certified manufacturing with consistent quality control.

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Frequently Asked Questions

Common questions about product usage, storage, and bulk ordering.

How accurate are the test results?

Our rapid test kits demonstrate 99% sensitivity and 98.8% specificity in clinical trials, ensuring highly accurate diagnostic results for veterinary professionals.

What is the shelf life and storage requirement?

The product has a 24-month shelf life when stored at 2-30°C. Room temperature storage makes it convenient for field use without refrigeration requirements.

What are the minimum order quantities for bulk purchases?

Minimum order quantities vary by product and customization requirements. Contact our sales team for specific MOQ information and volume pricing tiers.

Do you provide OEM/ODM services?

Yes, we offer comprehensive OEM/ODM services including custom packaging, private labeling, and product modifications to meet specific market requirements.

What shipping options are available for international orders?

We provide worldwide shipping with express delivery options. Our logistics team handles all documentation and ensures proper cold chain management when required.

Still have questions? Our technical support team is here to help.